The patient meditates for at least 30 minutes daily using a practice called "centering prayer," which he learned during his brief time as a postulate in a Franciscan monastery 37 years ago. In this technique, he focuses his mind on a single religious word to reach a meditative state. He states that he feels less "PD like" when he meditates, so he began to reinvest energy in meditation practice after his PD onset.
We are unable to offer insight as to why the patient presented with PD in the face of such possible benefits of long-term meditation practice; however, intensity of engagement with the practice likely increased after the diagnosis, and he may have benefited from this more intensive practice. Regardless of the role of the patient's meditation, this case demonstrates the possibility of PD symptom remission.
Dense modulatory projections from the ventromedial and orbito-prefrontal areas primarily influence the ventral striatum, the rostral caudate nucleus, and the putamen; additional sensorimotor area project more caudally primarily to the putamen.