“Did we miss something? Is it conceivable that for 40 years we have overlooked an insidious long-term levodopa treatment adverse effect, such as neuropathy, in idiopathic Parkinson's disease?" -- from the online journal "Neurology"
"This intriguing study demonstrates a somewhat unexpectedly high prevalence of peripheral neuropathy in Parkinson's disease patients…. Peripheral neuropathy in Parkinson's disease could substantially contribute to gait disturbances and disability in some patients with Parkinson's, and prevention of peripheral neuropathy would be an important advance." -- from the online journal "Medscape"
Toward the end of this past “Summer from Hell,” I started to wonder if some of the malaise I was experiencing might be due to something other than Washington's summer heat and humidity. As I mentioned in a recent post, one of my questions was: “Might I be experiencing peripheral neuropathy (PN)?"
Normal values for vitamin B12 are 200 to 900 picograms per milliliter (pg/mL). Older adults with vitamin B12 levels between 200 and 500 pg/mL may also have signs of vitamin B12 deficiency. My reading was 346 pg/mL
Peripheral neuropathy, a result of damage to your peripheral nerves, often causes weakness, numbness and pain, usually in your hands and feet. It can also affect other areas of your body.
Your peripheral nervous system sends information from your brain and spinal cord (central nervous system) to the rest of your body. Peripheral neuropathy can result from traumatic injuries, infections, metabolic problems, inherited causes and exposure to toxins. One of the most common causes is diabetes mellitus.
People with peripheral neuropathy generally describe the pain as stabbing, burning or tingling. In many cases, symptoms improve, especially if caused by a treatable condition. Medications can reduce the pain of peripheral neuropathy.
Alpha-lipoic acid. This has been used as a treatment for peripheral neuropathy in Europe for years. Discuss alpha-lipoic acid with your doctor because it can affect blood sugar levels. Other side effects can include stomach upset and skin rash.